RFX2 Transcription Factor Activity Assay

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SKU:
TFAB00156
€699

Description

ELISA Kit Technical ManualMSDS

RFX2 Transcription Factor activity assay

Product Description:The ELISA Genie RFX2 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates ELISA Genie ELISA kits are designed to significantly reduce experiment Time: and ensure sensitivity and flexibility for high-throughput screening.
Target Synonyms:
Detection Target:Phospho-IRAK1(Thr209)
Reactivity:Human, Mouse, Rat
Pack Size:12 x 8-Well Microstrips
Detection Method:Colorimetric 450 nm
Format:transcription factor activity assay
Storage and Stability Guarantee:4°C/6 Months
Sample Type:Nuclear or cell lysates
Range:See Technical Manual
Time:4.5 hours

RFX2 Transcription Factor activity assay Protein Information

UniProt Protein Function:RFX2: a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cytoplasm; nucleus

Molecular Function:DNA binding; transcription factor activity

Biological Process: acrosome formation; cilium biogenesis; regulation of transcription from RNA polymerase II promoter; spermatid development

NCBI Summary:This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]
UniProt Code:P48378
NCBI GenInfo Identifier:254763325
NCBI Gene ID:5990
NCBI Accession:P48378.2
UniProt Secondary Accession:P48378,Q6IQ44, Q8SNA2, A8K581, B3KNC4,
UniProt Related Accession:P48378
Molecular Weight:77,268 Da
NCBI Full Name:DNA-binding protein RFX2
NCBI Synonym Full Names:regulatory factor X2
NCBI Official Symbol:RFX2
NCBI Protein Information:DNA-binding protein RFX2
UniProt Protein Name:DNA-binding protein RFX2
UniProt Synonym Protein Names:Regulatory factor X 2
Protein Family:RFX-like DNA-binding protein
UniProt Gene Name:RFX2
UniProt Entry Name:RFX2_HUMAN
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