In 2006, upon completion of the Human Genome Project, it was discovered that nearly 8% of the human genome is made up of viral DNA. These viral remnants are composed of ancient germline infections known as human endogenous retroviruses (HERVs) which are passed on to future generations in a Mendelian fashion1–4. Although these viral elements were previously thought to be ‘junk DNA’ or DNA with no functions in the body, research has slowly been emerging over the years that show that these viral
Sarah Brun Bar-Yaacov PhD Candidate, University of Liverpool
Orthohantaviruses are a group of segmented negative-sense RNA viruses maintained as asymptomatic infections in rodent, insectivore and bat populations (Vaheri, Strandin, et al. 2013). They are Bunyaviruses and to date 41 orthohantavirus species have been officially recognized (ICTV 2014). Among orthohantaviruses, the rodent-borne are the most studied, as these are the only ones associated with human disease.
Orthohantaviruses are f
A calculated balance between Virus Replication, Cell Proliferation and Host Immune System
HIV Virus: Replication Cycle and Pathogenesis in absence of HAART
Human immunodeficiency virus (HIV) is transmitted through body fluids (blood, sexual fluids, and breast milk) and causes acquired immunodeficiency syndrome (AIDS). Current highly active antiretroviral therapy (HAART) effectively suppresses virus replication preventing disease progression and mortality. Virus eradication has still to