Zebrafish against cretinism and hypotonia

By Natalia Siomava, PhD Cretinism is a severe medical condition of intellectual disability caused by the deficiency of thyroid hormone (congenital hypothyroidism). Severe thyroid deficiency or maternal hypothyroidism has been reported in numerous countries all over the world. It is common in areas with iodine-deficient soils (Kapil, 2007). However, each year a greater number of infants […]

Neglected Tropical Diseases

By Juan Quintana, PhD student, University of Edinbrugh What are Neglected Tropical Diseases (NTDs)? The World Health Organization (WHO) defines NTDs as a group of communicable, poverty-promoting diseases, which affect more than one billion people worldwide (Herricks et al., 2017). These diseases are primarily concentrated in sub-Saharan Africa, as well as in regions of South […]

SOCS proteins: Manipulating the immune response

By Katherine Edwards, PhD Student, Queen’s University Belfast Cytokines play a vital role in immune responses enabling cross-talk between different cell types and inducing activation, differentiation, proliferation and cell migration by altering gene expression in target cell types. There are a wide variety of cytokines each with varying roles which when produced in different combinations […]

Why are some of us tall, others short? why do we stop growing?

By Jasmin Imran Alsouis Why are some of us tall, others short? why do we stop growing? and why are we born with seemingly large heads and small limbs, but mature into adults with opposite proportions? In other words, what determines the absolute size of an organism and the relative sizes of its parts? These […]

Mononuclear Phagocytes in Health and Disease

By Amit Patel, PhD student at UCL Have you ever squeezed a spot and wondered what the white pus is? Or have you ever questioned the science behind tattoos? Breaking out in spots is an inflammatory reaction where immune cells travel to the site of infection or injury performing immune function to restore homeostasis.  Similarly, […]

Fluorescence spectroscopy: An early detection tool for cancer.

By Sunil Ajit Shah, Ph.D. candidate at University of North Texas Health Science Center, Fort Worth, TX. Millions of people are afflicted with cancer each year. 2016 statistics for the USA alone show over half a million deaths attributed to cancer1. We have come a long way from our early understanding of cancer, and now […]

13+ Crucial Tips to Prepare for a Successful PhD Interview

Before we get into the tips, it is important to note that not all PhD programs require an interview. It is definitely not something that you should dread or fear. It is all just part of the process and should not become an overwhelming factor. There are however steps you can take to make it […]

Autophagy alterations in Alzheimer’s disease

By Diana-Madalina Stan, PhD student, University of Salford Disease description Alzheimer’s disease (AD), the most common cause of dementia, is a neurodegenerative disorder that mainly affects the elderly. AD International reported 46.8 million people suffering from AD in 2015 and the number is presumed to be 50 million at present. AD pathology includes abnormal protein […]

Imposter syndrome during the first year of my PhD

By Harry Potter, PhD Candidate, University of Manchaster “As a freshly minted grad student sat in the back row of a University lecture theatre bearing the name of a Nobel laureate, I had a revelation. I finally had a name to attach to that innate feeling which I had first experienced over a decade ago […]

Follicle Stem Cell Behaviour

By David Melamed, Phd Candidate, Colombia University When I started in the Kalderon Lab five years ago, I had no idea that our work would lead us to drastically revise an entire model system of adult stem cell behavior. I joined the lab straight out of college, setting forth with a wide-eyed passion for stem […]